Omi – the Automated Organ-on-Chip Platform
A one-of-a-kind innovative Platform
SDR Scientific is the sole distributor for Fluigent within Australia and New Zealand. Based in France, Fluigent develops, manufactures and supports a range of novel microfluidic systems.
Applications
Omi is the perfect automated organ-on-chip platform for any organ-on-a-chip application. It allows the simulation of any organ model, and by pairing several Omi together, one can model different interfaces for modeling of human organs.
The Omi is ideal for drug discovery, ADME-Tox, and other disease models.
Single or Double Channel Configuration: It’s your Choice!
* Single Channel Configuration
- Blood Vessel Reproduction
- Study drug transport or nutrient absorption with endothelial cells-on-chip with Omi.
- Cancer Drug Discovery
- Mimic the effect of drug compounds on tumor cells to evaluate their response to the treatments.
* Double Channel Configuration
- Liquid / Liquid interface
- Omi’s fluidic system allows, when paired in 2, to model liquid-liquid interfaces to reproduce
- physiological functions of different human organs.
- Blood-brain-Barrier
- Assess vascular permeability using our platform and brain cells-on-chip. Our microfluidic functionalities and protocols allow for accurate cell organization and physiology to study the microenvironment of the human brain.
- Gut-on-chip: Study drug absorption and interaction with endothelial cells in gut-on-chip models with Omi’s fluidic functionalities. Inject new nutrients or drugs and analyze cell behavior by sampling the medium.
Key Features & Benefits:
- Fully integrated platform: Omi can perform user customized protocol including perfusion, recirculation, injection and sampling.
- Compact and transportable: The device is designed to fit in incubators and can be easily transported to a microscope for imaging or cell analysis while maintaining perfusion.
- Remote control: Set up and monitor your protocols on Omi’s application’s user friendly interface with WIFI.
- Contamination-free: Inject cell or fresh medium, deliver test compounds, collect samples without disconnecting the microfluidic chip and disturbing the shear stress conditions of the experiments.
- Completely autonomous platform: 2-hour battery allows for transport from incubator to imaging system.
Reproducibility and exNew Omi: Reproducibilty and experiment duplication have never been made this easy…riment duplication have never been this easy!
Links to source webpages
https://www.fluigent.com/research/instruments/automated-organ-on-chip-platform/
Links to White Paper
https://www.fluigent.com/resources-support/expertise/white-papers/review-a-guide-to-organs-on-chips/
Links to References
https://www.vecer.com/priloge/cudno-a-obetavno-10267977
http://www.bosa.co.kr/news/articleView.html?idxno=2167206
https://www.isna.ir/news/1400110201185/%D8%AF%DA%AF%D8%B1%D8%AF%DB%8C%D8%B3%DB%8C-%D8%AF%D8%B1-%D9%81%D9%86%D8%A7%D9%88%D8%B1%DB%8C